Metabolic activity (short chain fatty acid (SCFA) acetic acid, propionic acid and butyric acid) and lactic acid of the microbial community in reactor three, four and five from the basal, treatment and washout periods in the SHIME
. Reactor 3: simulates the ascending colon; reactor 4: simulates the transverse colon; reactor 4: simulates the descending colon. Statistically significant differences among the samples were investigated with one-way ANOVA. Samples with the same letter on the top of the bar are not statistically different, (p < 0.01).