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Table 7 Risk of rs2607474 GG homozygote in H. pylori positive or negative subjects

From: Influence of HRH2 promoter polymorphism on aberrant DNA methylation of DAPK and CDH1in the gastric epithelium

DAPK methylation      
H. pylori negative (189) GG GA AA GG vs GA + AA; OR (95%CI) p value
unmethylated (109) 73 35 1 reference -
methylated (80) 67 12 1 2.70 (1.31-5.57) 0.0074
H. pylori positive (338)      
unmethylated (122) 82 37 3 reference -
methylated (216) 179 35 2 2.29 (1.36-3.86) 0.0018
CDH1 gene methylation      
H. pylori negative (189) GG GA AA GG vs A carrier; OR (95%C.I.) p value
unmethylated (129) 86 41 2 reference -
methylated (60) 54 6 0 4.43 (1.76-11.1) 0.0016
H. pylori positive (338)      
unmethylated (152) 111 37 4 reference -
methylated (186) 150 35 1 1.50 (0.900-2.51) 0.12
  1. by logistic regression analysis after adjustment for age and gender.
  2. (): the number of subjects.
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BMC Gastroenterology

ISSN: 1471-230X

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