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Table 6 Risk of rs2697474 GG homozygote in younger or older subjects

From: Influence of HRH2 promoter polymorphism on aberrant DNA methylation of DAPK and CDH1in the gastric epithelium

DAPK methylation      
= < 60 (233) GG GA AA GG vs GA + AA; OR (95%CI) p value
unmethylated (115) 80 32 3 reference -
methylated (118) 96 21 1 2.12 (1.13-3.98) 0.020
60 < (294)      
unmethylated (116) 75 40 1 reference -
methylated (178) 150 26 2 2.72 (1.55-4.80) 0.0005
CDH1 methylation      
= < 60 (233) GG GA AA GG vs A carrier; OR (95%C.I.) p value
unmethylated (121) 88 29 4 reference -
methylated (112) 88 24 0 1.55 (0.827-2.91) 0.17
60 < (294)      
unmethylated (160) 109 49 2 reference -
methylated (134) 116 17 1 2.81 (1.53-5.17) 0.0009
  1. by logistic regression analysis after adjustment for age, gender and H. pylori infection status.
  2. (): the number of subjects.