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Table 4 Risk of −1018 GG homozygote for the development of DAPK methylation

From: Influence of HRH2 promoter polymorphism on aberrant DNA methylation of DAPK and CDH1in the gastric epithelium

Overall (527) GG GA AA GG vs A carrier; OR (95%C.I.) p value
unmethylated (231) 155 72 4 reference -
methylated (296) 246 47 3 2.43 (1.60-3.69) <0.0001
non-GC (412)      
unmethylated (211) 138 69 4 reference -
methylated (201) 167 31 3 2.61 (1.62-4.20) <0.0001
GC (115)      
(non cancerous mucosa)      
unmethylated (20) 17 3 0 reference -
methylated (95) 79 16 0 0.825 (0.379-3.73) 0.78
(cancer lesion)      
unmethylated (11) 10 1 0 reference -
methylated (104) 86 18 0 0.598 (0.069-5.19) 0.64
  1. by logistic regression analysis after adjustment for age, gender and H. pylori infection status.
  2. (): the number of subjects.