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Table 3 The frequencies of genotypes among CDH1 methylated and unmethylated groups

From: Influence of HRH2 promoter polymorphism on aberrant DNA methylation of DAPK and CDH1in the gastric epithelium

  CDH1 unmethylated CDH1 methylated p value*
the number of subjects 281 246  
mean age ± SD 60.6 ± 14.0 61.4 ± 13.3 NS
male : female 165 : 116 154 : 92 NS
H. pylori positivity 152/281 186/246 <0.0001
non-GC : GC 262 : 19 150 : 96 <0.0001
HRH2 rs2607474 genotype    
G/G 197 204 0.013#
G/A 78 41  
A/A 6 1  
A allele frequency 16.0% 8.7% 0.0004
  1. *: unmethylated vs. methylated, #: frequency of GG homozygote.
  2. NS: not significant.