Table 3 The frequencies of genotypes among CDH1 methylated and unmethylated groups

the number of subjects

281

246

mean age ± SD

60.6 ± 14.0

61.4 ± 13.3

NS

male : female

165 : 116

154 : 92

NS

H. pylori positivity

152/281

186/246

<0.0001

non-GC : GC

262 : 19

150 : 96

<0.0001

HRH2 rs2607474 genotype

G/G

197

204

0.013#

G/A

78

41

A/A

6

1

A allele frequency

16.0%

8.7%

0.0004