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Table 2 The frequencies of genotypes among DAPK methylated and unmethylated groups

From: Influence of HRH2 promoter polymorphism on aberrant DNA methylation of DAPK and CDH1in the gastric epithelium

 

DAPK unmethylated

DAPK methylated

p value*

the number of subjects

231

296

 

mean age ± SD

59.6 ± 13.4

62.1 ± 13.8

0.035

male : female

137 : 94

182 : 114

NS

H. pylori positivity

122/231

216/296

<0.0001

non-GC : GC

211 : 20

201 : 95

<0.0001

HRH2 rs2607474 genotype

   

GG

155

246

<0.0001#

GA

72

47

 

AA

4

3

 

A allele frequency

17.3%

9.0%

<0.0001

  1. *: unmethylated vs. methylated, #: frequency of GG homozygote.
  2. NS: not significant.