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Table 2 The frequencies of genotypes among DAPK methylated and unmethylated groups

From: Influence of HRH2 promoter polymorphism on aberrant DNA methylation of DAPK and CDH1in the gastric epithelium

  DAPK unmethylated DAPK methylated p value*
the number of subjects 231 296  
mean age ± SD 59.6 ± 13.4 62.1 ± 13.8 0.035
male : female 137 : 94 182 : 114 NS
H. pylori positivity 122/231 216/296 <0.0001
non-GC : GC 211 : 20 201 : 95 <0.0001
HRH2 rs2607474 genotype    
GG 155 246 <0.0001#
GA 72 47  
AA 4 3  
A allele frequency 17.3% 9.0% <0.0001
  1. *: unmethylated vs. methylated, #: frequency of GG homozygote.
  2. NS: not significant.