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Table 1 Characteristics of the subjects and the PTPN11 polymorphisms

From: Association of polymorphism of PTPN 11 encoding SHP-2 with gastric atrophy but not gastric cancer in Helicobacter pylori seropositive Chinese population

  Gastric cancer (%) Gastric atrophy (%) Control(%) P value (%)
N 414 109 923  
Sex     
Male 300(72.5) 64(58.7) 539(58.4) <0.001
Female 114(27.5) 45(41.3) 384(41.6)  
Age     
≤45 32(7.7) 19(17.4) 276(29.9) <0.001
46-65 224(54.1) 80(73.4) 579(62.7)  
>65 158(38.2) 10(9.2) 68(7.4)  
Anti-H.pylori IgG     
Negative 123(29.7) 27(24.8) 464(50.3) <0.001
Postive 291(70.3) 82(75.2) 459(49.7)  
SNPs     
rs2301756     
GG 305(73.7) 86(78.9) 687(74.4) 0.462
GA 95(22.9) 22(20.2) 216(23.4)  
AA 14(3.4) 1(0.9) 20(2.2)  
rs12423190     
TT 214(51.7) 55(50.5) 476(51.6) 0.047
TC 166(40.1) 36(33.0) 373(40.4)  
CC 34(8.2) 18(16.5) 74(8.0)  
rs12229892     
GG 137(33.1) 40(36.7) 308(33.4) 0.963
GA 205(49.5) 50(45.9) 454(49.2)  
AA 72(17.4) 19(17.4) 161(17.4)  
rs7958372     
TT 305(73.7) 87(79.8) 685(74.2) 0.747
TC 102(24.6) 21(19.3) 222(24.1)  
CC 7(1.7) 1(0.9) 16(1.7)  
rs4767860     
AA 137(33.1) 39(35.8) 306(33.2) 0.386
AG 206(49.8) 44(40.4) 453(49.1)  
GG 71(17.1) 26(23.9) 164(17.8)