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Table 1 Comparison of baseline characteristics (a) between individuals with and without fatty liver at baseline and (b) between individuals with and without incident fatty liver at follow up

From: Predicting incident fatty liver using simple cardio-metabolic risk factors at baseline

  Baseline fatty liver status (a) Follow up fatty liver status (b)
  Absent Present (a) Absent Present (b)
    p value    p value
n 2589 988   2159 430  
Age (y) 46.27 ± 8.51 48.08 ± 8.69 <0.0001 46.06 ± 8.57 47.32 ± 8.11 0.005
% Men 1305(50.4%) 800(81.0%) <0.0001 999 (46.3%) 306 (71.2%) <0.0001
BMI (kg/m2) 22.94 ± 2.58 26.10 ± 2.42 <0.0001 22.66 ± 2.53 24.33 ± 2.32 <0.0001
Waist 77.00 ± 8.44 87.52 ± 6.68 <0.0001 75.93 ± 8.25 82.36 ± 7.22 <0.0001
Exercise       
None 817(31.5%) 270(27.3%) .002 689 (31.9%) 128 (29.8%) 0.81
≤1time/week 359(13.9%) 183(18.5%)   297 (13.8%) 62 (14.4%)  
>1time/week 1413(54.6%) 535(54.1%)   1173 (54.3%) 240 (55.8%)  
% Smoker       
Never 1821(70.3%) 490(49.6%) <0.0001 1581 (73.2%) 240 (55.8%) <0.0001
Past 293(11.3%) 238(24.1%)   215 (10.0%) 78 (18.1%)  
Current 475(18.3%) 260(26.3%)   363 (16.8%) 112 (26.0%)  
Alcohol (gm/day) 5.81 ± 7.07 7.68 ± 7.53 <0.0001 5.37 ± 6.82 8.01 ± 7.84 <0.0001
SBP (mmHg) 115.23 ± 13.82 112.39 ± 15.00 <0.0001 114.60 ± 13.49 118.36 ± 14.97 <0.0001
DBP (mmHg) 74.64 ± 9.89 80.08 ± 10.08 <0.0001 74.06 ± 9.71 77.53 ± 10.25 <0.0001
Triglyceride
(mmol/L)
Median
[IQR]
1.10
[0.80,1.51]
1.80
[1.33,2.44]
<0.0001 1.04
[0.77,1.41]
1.38
[1.04,1.91]
<0.0001
HDL-C (mmol/L) 1.54 ± 0.30 1.40 ± 0.23 <0.0001 1.56 ± 0.31 1.47 ± 0.27 <0.0001
HsCRP (mg/L) 0.82 ± 1.43 1.38 ± 1.75 <0.0001 0.77 ± 1.40 1.03 ± 1.58 <0.0001
Platelets (109/L) 246.14 ± 53.10 235.32 ± 50.57 <0.0001 244.73 ± 52.63 253.16 ± 54.90 0.003
Albumin (g/L) 45.6 ± 2.4 46.7 ± 2.5 <0.0001 45.4 ± 3.0 45.9 ± .2.3 <0.0001
ALT (U/L) 21.44 ± 15.19 38.39 ± 22.02 <0.0001 20.38 ± 11.67 26.69 ± 25.95 <0.0001
AST (U/L) 22.14 ± 7.11 27.99 ± 10.87 <0.0001 21.87 ± 6.93 23.46 ± 7.83 <0.0001
AST/ALT ratio 1.17 ± 0.36 0.82 ± 0.27 <0.0001 1.19 ± 0.36 1.03 ± 0.33 <0.0001
AST/platelet index 9.46 ± 3.97 11.62 ± 5.81 <0.0001 9.38 ± 3.74 9.86 ± 4.95 0.06
Fasting Glucose
(mmol/L)
5.10 ± 0.66 5.55 ± 1.13 <0.0001 5.06 ± 0.56 5.26 ± 1.01 <0.0001
Fasting Insulin (pmol/L) 59.48 ± 18.65 75.39 ± 27.89 <0.0001 58.91 ± 18.18 62.28 ± 20.64 0.002
HOMA-IR 1.95 ± 0.69 2.69 ± 1.16 <0.0001 1.92 ± 0.66 2.10 ± 0.81 <0.0001
MetS, n (%) 135 (5.2%) 293 (29.7%) <0.0001 92 (4.3%) 43 (10.0%) <0.0001
  1. Data are presented as mean (SD), except where indicated.