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Table 3 Biological processes associated with identified proteins with references to results obtained in earlier studies

From: Comparative analysis of inflamed and non-inflamed colon biopsies reveals strong proteomic inflammation profile in patients with ulcerative colitis

Biological process Protein name
Energy generation triosephosphate isomerase1,3,4, glycerol-3-phosphate-dehydrogenase, alpha enolase2,3, isocitrate dehydrogenase, L-lactate dehydrogenase B-chain, inorganic pyrophosphatase, enoyl-CoA hydratase
Response to oxidative stress selenium binding protein1,2, superoxide dismutase, thioredoxin-dependent peroxide reductase1, peroxiredoxin-14, peroxiredoxin-4, peroxiredoxin-6
Stress response proteins Alpha-enolase3, Hsp601,3, Hsp701,4
  1. 1Different protein level between diseased UC versus normal colon mucosa tissues using colon biopsies [22]. 2Different protein level between inflamed and non-inflamed tissue regions in single UC patients as identified in purified epithelial cells from biopsies [19]. 3Different protein level in mucosal tissue biopsies from patients with chronic refractory pouchitis before and after antibiotic/probiotic therapy [34]. 4Different protein level between intestinal epithelial cells from healthy subjects and CD patients [35].