Skip to main content

Table 2 List of additional significant proteins identified in UC patients

From: Comparative analysis of inflamed and non-inflamed colon biopsies reveals strong proteomic inflammation profile in patients with ulcerative colitis

Spot Protein Name SwissProt Acc.no. S cov %1 pI2 Mw2 Fold diff.3  T -test (p)4
Higher level in RE
15 Superoxide dismutase P04179 61a 7.0 22 1.9 1.076e-007
16 Peroxiredoxin-4 Q13162 59a 5.8 31 1.7 1.510e-006
17 F-actin capping protein subunit alpha-1 P52907 44a 5.5 33 1.6 8.491e-005
18 Inorganic Pyrophosphatase Q15181 48a 5.5 33 1.4 1.461e-004
19 Triosephosphate isomerase P60174 48a 7.7 27 2.0 3.173e-004
20 Actin cytoplasmic P60709 62a 5.2 42 1.8 5.368e-004
21 Thiosulfate sulfurtransferase Q16762 49a 6.9 34 1.3 0.004
22 Serum albumin P02768 16a 5.9 71 1.4 0.005
23 Serum albumin P02768 5a 5.9 71 1.8 0.005
24 Proteasome activator Q9UL46 53a 5.4 28 1.2 0.005
25 Serotransferrin P02787 24a 7.0 79 1.4 0.014
26 F-actin capping protein subunit beta P47756 45a 5.6 31 1.1 0.025
Lower level in RE
27 Selenium binding protein Q13228 60a 5.9 53 1.4 1.525e-006
28 Protein ETHE1 O95571 56a 6.4 28 1.4 2.911e-006
29 Enoyl-CoA hydratase P30084 46a 9.4 32 1.3 7.862e-006
30 Isocitrate dehydrogenase O75874 35a 6.6 47 1.7 9.730e-006
31 Elongation factor Tu P49411 52a 7.9 50 1.4 2.055e-005
32 Peroxiredoxin-6 P30041 63a 6.0 25 1.4 8.820e-005
33 Tubulin alpha-6 chain Q9BQE3 29a 4.8 50   4.100e-005
34 Carbonic anhydrase 1 P00915 46a 6.7 29 2.0 1.354e-004
35 Annexin A1 P04083 34 6.7 39 1.3 2.942e-004
36 Cathepsin D P07339 33a 6.1 45 1.3 3.062e-004
37 Thioredoxin-dependent peroxide reductase P30048 55a 8.9 28 1.3 0.001
38 Heat shock protein 70 kDa /Serum albumin P08107/P02768 33a/66a 5.9/5.4 70/71 1.4 0.004
39 60 kDa heat shock protein P10809 41a 5.6 61 1.3 0.014
40 Serum albumin P02768 18a 5.9 71 1.3 0.019
41 Triosephosphate isomerase P60174 63a 6.5 27 1.3 0.019
42 Serum albumin P02768 20a 5.9 71 1.3 0.021
43 Alpha-enolase P06733 42a 7.7 47 1.1 0.042
  1. 1Percentage sequence coverage (S cov %) is followed by a if the mascot score was significant (P < 0.05). 2Theoretical isoelectric point (pI) and theoretical molecular weight (Mw) are presented. 3Fold difference in protein level. 4p-value from t-test. 5The protein was identified by MS/MS.