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Table 3 Pre-treatment biochemical tests of patients with high and low grades of liver inflammation

From: Extent of liver inflammation in predicting response to interferon α & Ribavirin in chronic hepatitis C patients: a cohort study

Study variable

High grades of inflammation

Low grades of inflammation

P- Value

 

n1

Response to variable

no

Response to variable

 

Pre-treatment Biochemical tests

ALT in U/L (mean ± SD)

87

119.2 ± 76.6

508

85.6 ± 66.6

<0.01 a

AST in U/L (median & IQR)

17

69 (22–229)

104

42 (14–508)

0.17b

Bilirubin in mg/dL (mean ± SD)

62

0.9 ± 0.3

370

0.9 ± 0.4

0.67a

Alkaline phosphatase in U/L (mean ± SD)

61

203 ± 131.6

356

207.3 ± 98.7

0.78a

Albumin in g/dL (mean ± SD)

29

3.0 ± 0.4

110

4.1 ± 0.4

0.04a

  1. a- Student’s t-test,b- Mann Whitney U test, n 1 : number of patients in High inflammation group, n o : number of patients in low inflammation group.