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Figure 5 | BMC Gastroenterology

Figure 5

From: Mitochondrial uncouplers inhibit hepatic stellate cell activation

Figure 5

FCCP and Valinomycin inhibit TGF-β signaling in 2 day old mHSCs. (A) Expression of pro-fibrogenic genes in cells treated for 24 hours with 5 μM of FCCP and Valinomycin or together with TGF-β (10 ng/mL) as indicated. (B) Expression of TGF-β early immediate genes Smad6 and Smad7 on HSCs treated for 2 hours with TGF-β. * indicates P < 0.05 compared to control groups and ** indicates P < 0.05 compared to TGF-β group. Data are expressed as means of 3 independent experiments ± SEM.

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