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Figure 4 | BMC Gastroenterology

Figure 4

From: GDNF protects enteric glia from apoptosis: evidence for an autocrine loop

Figure 4

Activation of caspase 3/7 in primary EGC cultures. Fluorometric detection of caspase 3/7 activity after incubation of the EGC cultures with TNF-α (100 ng/ml), IFN-γ (100 ng/ml) and GDNF (100 ng/ml), alone or in combination as described above. The bars indicate mean values ± SD, normalized to controls, three independent experiments were performed in duplicates (N = 3). Asterisk indicates a significant increase as compared to controls (p < 0.05).

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