Figure 4
From: GDNF protects enteric glia from apoptosis: evidence for an autocrine loop
Activation of caspase 3/7 in primary EGC cultures. Fluorometric detection of caspase 3/7 activity after incubation of the EGC cultures with TNF-α (100 ng/ml), IFN-γ (100 ng/ml) and GDNF (100 ng/ml), alone or in combination as described above. The bars indicate mean values ± SD, normalized to controls, three independent experiments were performed in duplicates (N = 3). Asterisk indicates a significant increase as compared to controls (p < 0.05).