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Table 2 Incidence and crude and adjusted rate ratios of inflammatory bowel disease in a retrospective cohort study of active duty US military personnel from 1998 to 2008

From: Risk of inflammatory bowel disease following a diagnosis of irritable bowel syndrome

 

All IBD

CD

UC

 

Incidence*

cRR (95% CI)

aRR (95% CI)

Incidence*

cRR (95% CI)

aRR (95% CI)

Incidence*

cRR (95% CI)

aRR (95% CI)

Female

81.5

1.0

1.0

23.3

1.0

1.0

46.6

1.0

1.0

Male

98.5

1.21 (0.74, 1.96)

2.21 (1.35, 3.62)

43.2

1.85 (0.78, 4.44)

3.55 (1.47, 8.54)

43.2

0.93 (0.48, 1.80)

1.66 (0.84, 3.28)

≤1 IGE

89.4

1.0

1.0

40.1

1.0

1.0

37.0

1.0

1.0

>1 IGE

274.7

3.07 (1.42, 6.64)

2.19 (1.01, 4.75)

196.2

4.90 (1.93, 12.42)

1.51 (0.36, 6.32)

78.5

2.12 (0.51, 8.81)

3.49 (1.36, 8.95)

Not deployed

104.3

1.0

1.0

40.5

1.0

1.0

49.8

1.0

1.0

Deployed

29.6

0.28 (0.10, 0.77)

0.33 (0.12, 0.91)

22.2

0.55 (0.17, 1.78)

0.65 (0.20, 2.13)

7.4

0.15 (0.02, 1.08)

0.17 (0.02, 1.27)

No IBS

27.8

1.0

1.0

7.3

1.0

1.0

16.1

1.0

1.0

IBS

238.1

8.56 (5.18, 14.17)

9.40 (5.64, 15.6)

104.7

14.32 (5.59, 36.67)

17.30 (6.71, 44.62)

104.7

6.51 (3.29, 12.88)

6.53 (3.25, 13.11)

  1. * Per 100,000 person-years.
  2. IBD: inflammatory bowel disease; CD: Crohn’s disease; UC: ulcerative colitis; cRR: crude rate ratio; aRR: adjusted rate ratio; CI: confidence interval.