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Table 3 Test characteristics of fecal calprotectin to predict a clinically significant gastrointestinal finding

From: Value of fecal calprotectin in the evaluation of patients with abdominal discomfort: an observational study

Clinically significant finding AUC (95%CI) Cut-off (μg/g) Sens
(%)
Spec
(%)
LR+ LR- NPV (%) PPV (%) Accuracy (%)
Overall 0.877 (0.85 - 0.90) 50 73 93 10.8 0.29 88 84 85
Upper gastrointestinal tract 0.730 (0.66 - 0.79) 48 59 82 3.2 0.50 75 68 71
Lower gastrointestinal tract 0.912 (0.88 - 0.94) 50 84 92 10.6 0.17 82 93 89
  1. Area under the receiver operating characteristics curve (AUC) with corresponding sensitivity (Sens), specificity (Spec), positive and negative likelihood ratio (LR+, LR-), and negative and positive predictive values (NPV, PPV) for fecal calprotectin to identify a clinically significant finding in the gastrointestinal tract. Overall accuracy was calculated using the following formula: (true positive test results + true negative test results)/total population.