Clinically significant finding
|
AUC (95%CI)
|
Cut-off (μg/g)
|
Sens
(%)
|
Spec
(%)
|
LR+
|
LR-
|
NPV (%)
|
PPV (%)
|
Accuracy (%)
|
---|
Overall
|
0.877 (0.85 - 0.90)
|
50
|
73
|
93
|
10.8
|
0.29
|
88
|
84
|
85
|
Upper gastrointestinal tract
|
0.730 (0.66 - 0.79)
|
48
|
59
|
82
|
3.2
|
0.50
|
75
|
68
|
71
|
Lower gastrointestinal tract
|
0.912 (0.88 - 0.94)
|
50
|
84
|
92
|
10.6
|
0.17
|
82
|
93
|
89
|
- Area under the receiver operating characteristics curve (AUC) with corresponding sensitivity (Sens), specificity (Spec), positive and negative likelihood ratio (LR+, LR-), and negative and positive predictive values (NPV, PPV) for fecal calprotectin to identify a clinically significant finding in the gastrointestinal tract. Overall accuracy was calculated using the following formula: (true positive test results + true negative test results)/total population.