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Table 1 Comparisons of biochemical laboratory bone markers among patients and controls

From: Fibroblast growth factor 23 contributes to diminished bone mineral density in childhood inflammatory bowel disease

  

Control (I)

UC Flare (IIa)

UC Remission (IIb)

IIa vs IIb t (p)

CD Flare (IIIa)

CD Remission (IIIb)

IIIa vs IIIb t (p)

BMD (g/cm2)

  

0.74 +/−0.14

0.91 +/−0.11

−5.15

0.73 +/−0.13

0.92 +/−0.12

−4.34

   

(<0.0001)

  

(<0.0001)

Z score for BMD

  

−3.47 +/−1.75

−1.02 +/−1.21

−5.97

−3.24 +/−2.20

0.06 +/−1.48

−5.57

   

(<0.0001)

  

(<0.0001)

25 (OH) VD3(ng/ml)

 

47.14+/−11.78

37.41 +/−16.69

40.96 +/−12.53

−0.89

34.40 +/−19.21

42.00 +/−15.49

−1.38

    

(0.38)

  

(0.176)

 

Comparison with control

T

2.27

−1.74

 

2.58

1.2

 
 

(p)

(0.028)

(0.089)

 

(0.014)

(0.237)

 

1, 25 (OH)2 VD3 (pg/ml)

 

30.86 +/−6.67

56.11 +/−12.11

30.96 +/−8.14

8.96

65.65+/−14.99

22.80+/−3.70

12.403

    

(<0.0001)

  

(<0.0001)

 

Comparison with control

T

8.59

0.05

 

9.68

−4.75

 
 

(p)

(<0.0001)

(0.96)

 

(<0.0001)

(<0.0001)

 

FGF23 (pg/ml)

 

16.90+/−4.91

62.22 +/−20.70

26.89 +/−8.83

8.157

67.75 +/−18.36

23.55 +/−9.95

9.465

    

(<0.0001)

  

(<0.0001)

 

Comparison with control

T

9.80

4.64

 

12.25

2.73

 
 

(p)

(<0.0001)

(<0.0001)

 

(<0.0001)

(0.009)

 

PTH

 

38.410 +/−19.98

67.71 +/−20.930

55.32 +/−17.23

0.81

62.62 +/−23.07

51.81+/−20.58

0.65

    

0.42

  

0.52

   

−5.01

−3.21

 

−3.68

−2.17

 
   

0.0001

0.002

 

0.001

0.036

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