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Table 1 Intestinal mucosal parameters

From: Dietary L-arginine supplementation reduces Methotrexate-induced intestinal mucosal injury in rat

  CONTR CONTR-ARG MTX MTX-ARG
Bowel weight     
(mg/cm/100 mg body weight)     
   Jejunum 23 ± 1 21 ± 1 17 ± 0.3 * 19 ± 1 *†
   Ileum 21 ± 1 19 ± 1 17 ± 1 * 21 ± 1 *†
Mucosal weight     
(mg/cm/100 mg body weight)     
   Jejunum 9.4 ± 0.5 7.6 ± 0.5 * 5.1 ± 0.6 * 6.2 ± 0.6
   Ileum 9.1 ± 0.5 6.7 ± 0.5 * 4.7 ± 0.5 * 6.1 ± 0.6 *†
Mucosal DNA     
(μg/cm/100 mg body weight)     
   Jejunum 45 ± 7 30 ± 4 * 22 ± 5 * 25 ± 3 *
   Ileum 47 ± 6 52 ± 4 19 ± 4 * 38 ± 9 †
Mucosal protein     
(μg/cm/100 mg body weight)     
   Jejunum 94 ± 21 60 ± 11 58 ± 10 * 58 ± 5 *
   Ileum 54 ± 10 44 ± 8 32 ± 5 * 51 ± 8 †
Villus height (μm)     
   Jejunum 434 ± 29 345 ± 56 314 ± 33 * 413 ± 18 †
   Ileum 371 ± 26 287 ± 19 * 217 ± 52 * 300 ± 23 *†
Crypt depth (μm)     
   Jejunum 183 ± 17 131 ± 8 * 112 ± 4 * 126 ± 11
   Ileum 161 ± 16 120 ± 8 * 101 ± 15 * 131 ± 10 *†
  1. CONTR- control, MTX-methotrexate, ARG-arginine
  2. * P < 0.05 All groups vs CONTR rats, † P < 0.05 MTX-ARG vs MTX rats.