Skip to main content
Figure 2 | BMC Gastroenterology

Figure 2

From: Dietary L-arginine supplementation reduces Methotrexate-induced intestinal mucosal injury in rat

Figure 2

Effects of MTX and arginine on crypt cell proliferation and apoptosis. The number of labeled cells in 10 well-oriented, longitudinal crypts per section from each rat was determined using light microscopy. Identification of apoptotic cells was performed using immunohistochemistry for Caspase-3. The apoptotic index is expressed as the percentage of apoptotic cells per 10 villi. Values are mean ± SEM. CONTR- control, MTX-methotrexate, ARG-arginine. * P < 0.05 MTX and MTX-ARG vs CONTR rats, † P < 0.05 MTX-ARG vs MTX rats.

Back to article page