Odds ratios (95% CI) | |||||
---|---|---|---|---|---|
Controls (%) | CRC (%) | P-value | Unadjusted | Adjusted* | |
any previous use | 68/132 (51.5) | 20/101 (19.8) | < 0.01 | 0.23 (0.13 – 0.42) | 0.43 (0.25 – 0.80) |
Duration | |||||
< 2 years | 14 (11%) | 8 (8) | 0.47 | 0.73 (0.56 – 3.43) | 0.66 (0.21 – 1.69) |
2 – 5 years | 23 (17) | 7 (7) | 0.05 | 0.35 (0.15 – 0.86) | 0.38 (0.14 – 1.01) |
> 5 years | 31 (24) | 5 (5) | < 0.01 | 0.17 (0.063 – 0.454) | 0.18 (0.06 – 0.55) |
Dose | |||||
< 40 mg/day | 28 (21) | 12 (12) | 0.14 | 0.50 (0.24 – 1.04) | 0.51 (0.21 – 1.24) |
= or>40 mg/day | 40 (30) | 8 (8) | < 0.01 | 0.20 (0.09 – 0.45) | 0.19 (0.07 – 0.47) |
statin type | |||||
simvastatin | 49 (37) | 14 (14) | < 0.01 | 0.27 (0.14 – 0.53) | 0.43 (0.10 – 0.73) |
other | 19 (14) | 6 (6) | 0.09 | 0.38 (0.14 – 0.98) | 0.49 (0.13 – 1.13) |