Table 3 Characteristics of study population 2 (n = 19)
Characteristics | Â | Â | Group2-A with lichen planus (n = 12) | Group2-AB without lichen planus (n = 7) | P value |
|---|---|---|---|---|---|
Age (mean ± SD), years |  |  | 64.83 ± 7.51 | 63.86 ± 10.57 | NS |
Sex (male/female) | Â | Â | 4/8 | 1/6 | NS |
Diagnosis of liver diseases | CH-C (CH-C post HCC) | Â | 10 (2), 83.33% | 7 (100%) | NS |
| Â | LC-C (LC-C post HCC) | Â | 2 (1), 16.67% | 0 (0%) | NS |
Viral factors | HCV RNA level (logIU/mL) | High | 12 (100%) | 7 (100%) | NS |
| Â | HCV genotype | 1b | 12 (100%) | 7 (100%) | NS |
| Â | Amino acid substitutions in the core region | aa 70 (wild type/non-wild) | 5/7 (41.67%/58.33%) | 2/5 (28.57%/71.43%) | NS |
| Â | Â | aa 91 (wild type/non-wild) | 6/6 (50.00%/50.00%) | 5/2 (71.43%/28.57%) | NS |
| Â | Â | aa 70 and 91(double-wild type/non-double-wild type) | 3/9 (25.00%/75.00%) | 1/6 (14.29%/85.71%) | NS |
| Â | Number of ISDR substituions | 0 (wild type) | 8 (66.67%) | 3 (42.86%) | NS |
| Â | Â | 1-3 (intermediate type) | 4 (33.33%) | 4 (57.14%) | NS |
Effect of previous IFN therapy (non-SVR) | Â | Â | 12 (100%) | 7 (100%) | NS |