Table 1 Demography and clinical features of patients enrolled
From: Prevalence of non Helicobacter pylori species in patients presenting with dyspepsia
PCR for H. pylori | PCR for H. heilmannii | PCR for H. felis | |||||||
|---|---|---|---|---|---|---|---|---|---|
Positive n = 142 | Negative n = 108 | P value | Positive n = 17 | Negative n = 233 | P value | Positive n = 10 | Negative n = 240 | P value | |
Age | |||||||||
18-39 years | 81(57) | 55(51) | 8(47) | 128(55) | 6(60) | 130(55) | |||
40-55 years | 53(37) | 35(32) | 0.02 | 7(41) | 81(35) | 0.82 | 3(30) | 85(35) | 0.93 |
56-75 years | 8(6) | 18(17) | 2(12) | 24(10) | 1(10) | 25(10) | |||
Gender | |||||||||
Male | 98(69) | 64(59) | 0.11 | 11(65) | 151(65) | 0.99 | 5(50) | 157(65) | 0.33 |
Female | 44(31) | 44(41) | 6(35) | 82(35) | 5(50) | 83(35) | |||
Ethnicity | |||||||||
Karachiite | 36(25) | 36(33) | 4(24) | 68(29) | 2(20) | 70(29) | |||
Quetta resident | 47(36) | 31(25) | 0.15 | 5(29) | 73(31) | 0.81 | 3(30) | 75(31) | 0.75 |
Afghan | 55(39) | 45(42) | 8(47) | 92(40) | 5(50) | 95(40) | |||
Crowding Index (CI) | |||||||||
0-1(low) | 59(41) | 39(36) | 5(29) | 93(40) | 5(50) | 93(39) | |||
2-4 (moderate) | 82(58) | 62(57) | 0.03 | 12(71) | 132(57) | 0.35 | 5(50) | 139(58) | 0.59 |
> 4 (crowding) | 1(1) | 7(7) | 0(0) | 8(3) | 0(0) | 8(3) | |||
Water supply | |||||||||
Municipal | 86(61) | 59(55) | 0.34 | 8(47) | 137(59) | 0.34 | 7(70) | 138(58) | 0.52 |
Boring Water | 56(39) | 49(45) | 9(53) | 96(41) | 3(30) | 102(42) | |||
EGD | |||||||||
Gastritis | 136(96) | 106(96) | 0.47 | 17(100) | 225(97) | 1 | 10(100) | 232(97) | 1 |
Duodenal ulcer | 6(4) | 2(4) | 0(0) | 8(3) | 0(0) | 8(3) | |||
Rapid Urease test (n = 90) | |||||||||
Positive | 42(88) | 15(36) | > 0.001 | 4(44) | 53(63) | 0.28 | 2(40) | 55(63) | 0.35 |
Negative | 6(12) | 27(64) | 5(56) | 28(37) | 3(60) | 30(37) | |||
Histopathology (n = 160) | |||||||||
Bacterial density | |||||||||
Occasional | 10(11) | 40(61) | 3(37) | 47(31) | 0(0) | 50(32) | |||
Few in some fields | 59(63) | 21(32) | > 0.001 | 2(25) | 78(51) | 0.27 | 4(80) | 76(49) | 0.14 |
Only 1/2 small clusters | 25(27) | 5(7) | 3(38) | 27(18) | 1(20) | 29(19) | |||
Inflammation type | |||||||||
Chronic | 41(44) | 47(71) | 0.001 | 5(63) | 83(55) | 0.73 | 2(40) | 86(55) | 0.66 |
Chronic active inflammation | 53(56) | 19(29) | 3(37) | 69(45) | 3(60) | 69(45) | |||
Lymphoid follicles | |||||||||
Positive | 14(15) | 8(12) | 0.73 | 0(0) | 22(14) | 0.30 | 0(0) | 22(14) | 0.47 |
Negative | 80(85) | 58(88) | 8(100) | 130(86) | 5(100) | 133(86) | |||
Intestinal metaplasia | |||||||||
Positive | 3(3) | 2(3) | 1.0 | 2(25) | 3(2) | 0.02 | 1(20) | 4(3) | 0.15 |
Negative | 91(97) | 64(97) | 6(75) | 149(98) | 4(80) | 151(97) | |||