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Table 1 Demography and clinical features of patients enrolled

From: Prevalence of non Helicobacter pylori species in patients presenting with dyspepsia

  PCR for H. pylori PCR for H. heilmannii PCR for H. felis
  Positive n = 142 Negative n = 108 P value Positive n = 17 Negative n = 233 P value Positive n = 10 Negative n = 240 P value
Age
   18-39 years 81(57) 55(51)   8(47) 128(55)   6(60) 130(55)  
   40-55 years 53(37) 35(32) 0.02 7(41) 81(35) 0.82 3(30) 85(35) 0.93
   56-75 years 8(6) 18(17)   2(12) 24(10)   1(10) 25(10)  
Gender
   Male 98(69) 64(59) 0.11 11(65) 151(65) 0.99 5(50) 157(65) 0.33
   Female 44(31) 44(41)   6(35) 82(35)   5(50) 83(35)  
Ethnicity
   Karachiite 36(25) 36(33)   4(24) 68(29)   2(20) 70(29)  
   Quetta resident 47(36) 31(25) 0.15 5(29) 73(31) 0.81 3(30) 75(31) 0.75
   Afghan 55(39) 45(42)   8(47) 92(40)   5(50) 95(40)  
Crowding Index (CI)
   0-1(low) 59(41) 39(36)   5(29) 93(40)   5(50) 93(39)  
   2-4 (moderate) 82(58) 62(57) 0.03 12(71) 132(57) 0.35 5(50) 139(58) 0.59
   > 4 (crowding) 1(1) 7(7)   0(0) 8(3)   0(0) 8(3)  
Water supply
   Municipal 86(61) 59(55) 0.34 8(47) 137(59) 0.34 7(70) 138(58) 0.52
   Boring Water 56(39) 49(45)   9(53) 96(41)   3(30) 102(42)  
EGD
   Gastritis 136(96) 106(96) 0.47 17(100) 225(97) 1 10(100) 232(97) 1
   Duodenal ulcer 6(4) 2(4)   0(0) 8(3)   0(0) 8(3)  
Rapid Urease test (n = 90)
   Positive 42(88) 15(36) > 0.001 4(44) 53(63) 0.28 2(40) 55(63) 0.35
   Negative 6(12) 27(64)   5(56) 28(37)   3(60) 30(37)  
Histopathology (n = 160)
Bacterial density
   Occasional 10(11) 40(61)   3(37) 47(31)   0(0) 50(32)  
   Few in some fields 59(63) 21(32) > 0.001 2(25) 78(51) 0.27 4(80) 76(49) 0.14
   Only 1/2 small clusters 25(27) 5(7)   3(38) 27(18)   1(20) 29(19)  
Inflammation type
   Chronic 41(44) 47(71) 0.001 5(63) 83(55) 0.73 2(40) 86(55) 0.66
   Chronic active inflammation 53(56) 19(29)   3(37) 69(45)   3(60) 69(45)  
Lymphoid follicles
   Positive 14(15) 8(12) 0.73 0(0) 22(14) 0.30 0(0) 22(14) 0.47
   Negative 80(85) 58(88)   8(100) 130(86)   5(100) 133(86)  
Intestinal metaplasia
   Positive 3(3) 2(3) 1.0 2(25) 3(2) 0.02 1(20) 4(3) 0.15
   Negative 91(97) 64(97)   6(75) 149(98)   4(80) 151(97)  
  1. Univariate analysis was performed by using the independent sample t-test, Pearson Chi-square or Fisher Exact test where appropriate. A P-value of < 0.05 was considered as statistically significant. *All the H. heilmannii and H. felis PCR positive patients were also positive for H. pylori PCR amplification.