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Table 1 Basic demographic and clinical characteristics of all enrolled patients

From: Intravenous non-high-dose pantoprazole is equally effective as high-dose pantoprazole in preventing rebleeding among low risk patients with a bleeding peptic ulcer after initial endoscopic hemostasis

Variables

Sustained Hemostasis (n = 324)

Rebleeding (n = 89)

p-value

Age (years)

64.8 ± 13.9

66.4 ± 13.2

0.812

Female gender, n (%)

87(26.8)

35(39.3)

0.022*

Hb (g/L)

96.7 ± 28.2

82.5 ± 24.1

< 0.001*

Creatinine

2.0 ± 2.3

3.6 ± 3.3

< 0.001*

Platelet (× 109/L)

197.4 ± 87.3

188.0 ± 129.0

0.031*

Use of NSAIDs, n (%)

29(9.0)

4(4.5)

0.170

Use of aspirin, n (%)

60(18.5)

9(10.1)

0.060

Use of clopidogrel, n (%)

38(11.7)

11(12.4)

0.870

Use of wafarin, n (%)

15(4.6)

5(5.6)

0.700

Shock on admission, n (%)

165(50.9)

53(59.6)

0.149

Coexisting illness, n (%)

   

CKD III to V

126(38.9)

63(70.8)

< 0.001*

COPD

22(6.8)

7(7.9)

0.725

CAD

62(19.1)

23(25.8)

0.166

DM

87(26.9)

37(41.6)

0.007*

CVA

54(16.7)

20(22.5)

0.206

Liver Cirrhosis

55(17.0)

12(13.5)

0.429

Rockall score

6.0 ± 1.6

6.8 ± 1.7

< 0.001*

Time to endoscope (h)

14.7 ± 13.6

18.5 ± 20.3

0.333

Ulcer size (cm)

1.0 ± 0.6

1.0 ± 0.6

0.884

Multiple ulcers, n (%)

105(32.4)

36(40.4)

0.156

High stigmata in Forrest classification, n (%)

316(97.5)

86(96.6)

0.640

PRBC BT(mL)

1203.2 ± 1640.4

2192.6 ± 2077.3

< 0.001*

Surgery, n (%)

1(0.3)

7(7.9)

< 0.001*

Hospital stay(days)

11.5 ± 13.5

29.9 ± 46.0

< 0.001*

Mortality, n (%)

22(6.8)

26(29.2)

< 0.001*

Bleeding related/Other causes

5/17

14/12

 
  1. Abbreviations: OR, odds ratio; CI, confidence interval; Hb, hemoglobin; CKD, chronic kidney disease; NSAID, nonsteriodal anti-inflammatory drug; PPI, proton-pump inhibitor; DM, diabetes mellitus type 2; COPD, chronic obstructive pulmonary disease; CAD, coronary artery disease; CVA, cerebrovascular accident; BT, blood transfusion. * p < 0.05