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Table 5 Categorized risk groups for advanced fibrosis according to combined FIB4 index and NAFLD fibrosis score (NFS).

From: Validation of the FIB4 index in a Japanese nonalcoholic fatty liver disease population

   FIB4 index
(cut-off values proposed by Sterling et al.)
Total
  Low cut-off point (< 1.45) Indeterminate
(1.45-3.25)
High cut-off point (> 3.25)  
NFS Low cut-off point (<-1.455) 283
[1 (0.4%)] a
42
[4 (9.5%)] a
3
[0 (0.0%)] a
328 (56.9%)
[5 (1.5%)]
  Indeterminate (-1.455-0.676) 53
[5 (9.4%)] a
122
[19 (15.6%)] b
31
[14 (45.2%)] c
206 (35.8%)
[38 (18.4%)]
  High cut-off point (> 0.676) 0 17
[4 (23.5%)] b
25
[17 (68.0%)] c
42 (7.3%)
[21 (50.0%)]
Total 336 (58.3%)
[6 (1.7%)]
181 (31.4%)
[27 (14.9%)]
59 (10.2%)
[31 (52.5%)}
576 (100%)
[64 (11.1%)]
  1. Total number of patients [stage 3-4 (%)]
  2. Patients were categorized into three groups, "low-risk" (< 10%) a, "intermediate-risk" (10-30%) b and "high-risk" (> 30%) c, based on the combination of FIB4 index and NFS.