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Table 3 Accuracy of noninvasive fibrosis marker panels.

From: Validation of the FIB4 index in a Japanese nonalcoholic fatty liver disease population

Fibrosis panel AUROC Cut-off values Sensitivity (%) Specificity (%) PPV (%) NPV (%)
FIB4 index 0.871 1.45 3.25 90 48 64 95 24 53 98 94
AST/ALT ratio (AAR) 0.788 0.8 1 66 48 76 92 26 44 95 94
AST to platelet ratio index (APRI) 0.823 1 67 81 31 95
Age-platelet index (AP index) 0.810 6 66 78 27 95
NAFLD fibrosis score 0.863 -1.455 0.676 92 33 63 96 24 50 98 92
BARD score 0.765 2 80 65 22 97
N score 0.715 2 80 58 19 96
  1. AUROC, area under the receiver operating characteristics curve; PPV, positive predictive value; NPV, negative predictive value