Table 1 Formulae for determining noninvasive marker panels for detection of liver fibrosis.

FIB4 index

$\left(\mathsf{\text{Age}}\left[\mathsf{\text{years}}\right]\times \mathsf{\text{AST}}\mathsf{\text{[IU/L]}}\right)∕\left(\mathsf{\text{platelet count}}\mathsf{\text{[1}}{\mathsf{\text{0}}}^9\mathsf{\text{/L]}}\times \sqrt{\mathsf{\text{ALT[IU/L]}}}\right)$

AST to ALT ratio (AAR)

AST/ALT

AST to platelet ratio index (APRI) ^a

([AST/ULN]/platelet count [10⁹/L]) × 100

Age-platelet index (AP index)

Age (years)

platelet count (10⁹/L)

< 30 = 0

< 225 = 0

30-39 = 1

200-224 = 1

40-49 = 2

175-199 = 2

50-59 = 3

150-174 = 3

60-69 = 4

125-149 = 4

≥ 70 = 5

< 125 = 5

Score is the sum of two (0-10)

NAFLD fibrosis score

-1.675 + 0.037 × age (years) + 0.094 ×BMI (kg/m²) + 1.13 × IFG/diabetes (yes = 1, no = 0) + 0.99 × AST/ALT - 0.013 × platelet count (× 10⁹/L) - 0.66 × albumin (g/dL).

BARD score

Scale 0-4

BMI ≥ 28 kg/m² = 1 point

AST/ALT ≥ 0.8 = 2 points

Diabetes = 1 point

N (Nippon) score

Scale 0-4

female sex = 1 point

older age (> 60 years) = 1 point

type 2 diabetes = 1 point

hypertension = 1 point