Additional corpus biopsy enhances the detection of Helicobacter pylori infection in a background of gastritis with atrophy

Table 3 H. pylori sensitivity and specificity depending on grade of body gastritis with atrophy

Ca degree of gastritis with atrophy at body	Normal to mild	Moderate to severe
n=164	n=141	n=23
CLOtest Antrum
Sensitivity	95.66 (88.62-98.60)	83.33 (50.88-97.06)
Specificity	100.00 (90.94-100.00)	100.00 (67.86-100.00)
PPV	100.00 (94.79-100.00)	100.00 (65.55-100.00)
NPV	92.45 (80.93-97.55)	84.61 (53.66-97.29)
Accuracy	97.16	91.30
CLOtest Body
Sensitivity	100.00 (95.00-100.00)	100.00 (69.87-100.00)
Specificity	100.00 (90.94-100.00)	100.00 (67.85-100.00)
PPV	100.00 (95.00-100.00)	100.00 (69.87-100.00)
NPV	100.00 (90.94-100.00)	100.00 (67.85-100.00)
Accuracy	100.00	100.00
CLOtest Antrum + Body
Sensitivity	100.00 (95.00-100.00)	100.00 (69.87-100.00)
Specificity	100.00 (90.94-100.00)	100.00 (67.85-100.00)
PPV	100.00 (95.00-100.00)	100.00 (69.87-100.00)
NPV	100.00 (90.94-100.00)	100.00 (67.85-100.00)
Accuracy	100.00	100.00
Histology Antrum
Sensitivity	96.74 (90.09-99.15)	83.33 (50.88-97.06)
Specificity	100.00 (90.94-100.00)	100.00 (67.86-100.00)
PPV	100.00 (94.84-100.00)	100.00 (65.55-100.00)
NPV	94.23 (83.08-98.50)	84.61 (53.66-97.29)
Accuracy	97.87	91.30
Histology Body
Sensitivity	100.00 (95.00-100.00)	91.67 (59.75-99.56)
Specificity	100.00 (90.94-100.00)	100.00 (67.86-100.00)
PPV	100.00 (95.00-100.00)	100.00 (67.86-100.00)
NPV	100.00 (90.94-100.00)	91.67 (59.75-99.56)
Accuracy	100.00	95.65
Histology Antrum + Body
Sensitivity	100.00 (95.00-100.00)	91.67 (59.75-99.56)
Specificity	100.00 (90.94-100.00)	100.00 (67.86-100.00)
PPV	100.00 (95.00-100.00)	100.00 (67.86-100.00)
NPV	100.00 (90.94-100.00)	91.67 (59.75-99.56)
Accuracy	100.00	95.65

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