Table 4 Frequencies of mutational load (ML) in microdissected targets by histological classification
Histological classification of microdissected targets | Level of Mutational load (ML) | ||
|---|---|---|---|
No ML | Low ML (1 low clonality – 2 high clonality) | High ML (> 2 high clonality) | |
Normal squamous | 74 (90%) | 8 (10%) | 0 (0%) |
Columnar | 47 (61%) | 30 (39%) | 0 (0%) |
Intestinal metaplasia | 48 (22%) | 159 (74%) | 9 (4%) |
Indefinite for dysplasia | 20 (14%) | 106 (77%) | 12 (9%) |
Low grade dysplasia | 0 (0%) | 22 (56%) | 17 (44%) |
High grade dysplasia | 0 (0%) | 1 (6%) | 15 (94%) |