Table 2 Summary of total mutations detected by each histological classification
Histological classification | Total microdissected targets tested | Average number of mutated loci detected per microdissected target | Average number of low/ligh clonality mutations detected per microdissected target | Average mutational load | |
|---|---|---|---|---|---|
Low | High | ||||
Normal Squamous | 82 | 0.1 | 0.1 | 0.0 | 0.1 |
Columnar | 77 | 0.6 | 0.6 | 0.0 | 0.3 |
Intestinal Metaplasia | 216 | 1.5 | 1.2 | 0.3 | 0.9 |
Indefinite for dysplasia | 138 | 2.0 | 1.7 | 0.3 | 1.1 |
Low grade dysplasia | 39 | 3.5 | 2.7 | 0.8 | 2.2 |
High grade dysplasia | 16 | 4.0 | 1.5 | 2.5 | 3.3 |