Table 1 Baseline characteristics of the patients (per protocol population)
Gaviscon® N = 120 | Omeprazole N = 121 | |
|---|---|---|
Age, years: mean (SD) | 46.3 (10.7) | 44.5 (12.2) |
Women: N (%) | 73 (60.8) | 65 (53.7) |
Weight, kg: mean (SD) | 73.3 (14.8) | 74.5 (16.1) |
BMI, kg/m2: mean (SD) | 26.0 (5.2) | 26.2 (4.7) |
BMI ≥ 30 kg/m2: N (%) | 19 (15.8) | 23 (19.0) |
GERD, time to diagnosis, years: mean (SD) | 4.7 (6.3) | 5.3 (7.3) |
History of upper endoscopy: N (%) | 34 (28.3) | 44 (36.4) |
Number of days with heartburn per week | ||
- 2: N (%) | 9 (7.5) | 6 (5.0) |
- 3: N (%) | 29 (24.2) | 24 (19.8) |
- 4: N (%) | 35 (29.2) | 27 (22.3) |
- 5: N (%) | 17 (14.2) | 28 (23.1) |
- 6: N (%) | 30 (25.0) | 36 (29.8) |
- Mean: N (SD) | 4.3 (1.3) | 4.5 (1.2) |
Heartburn | ||
- Mild: N (%) | 10 (8.3) | 15 (12.4) |
- Moderate: N (%) | 83 (69.2) | 73 (60.3) |
- Severe: N (%) | 27 (22.5) | 33 (27.3) |
Heartburn-related pain (VAS), mm: mean (SD) | 52 (22) | 53 (22) |
Systolic BP, mmHg: mean (SD) | 124.8 (10.8) | 125.4 (11.0) |
Diastolic BP, mmHg: mean (SD) | 74.4 (8.5) | 74.2 (8.2) |
Heart rate, beat/min: mean (SD) | 72.6 (7.5) | 72.1 (9.0) |
Smoking, Yes: N (%) | 26 (21.7) | 27 (22.3) |
Alcohol consumption, Yes: N (%) | 29 (24.2) | 37 (30.6) |
Living alone: N (%) | 25 (20.8) | 37 (30.6) |
In couple: N (%) | 95 (79.2) | 84 (69.4) |
Place of residence | ||
- Rural | 37 (30.8) | 37 (30.6) |
- Suburban | 35 (29.2) | 34 (28.1) |
- Town | 33 (27.5) | 25 (20.7) |
- City | 15 (12.5) | 25 (20.7) |
Occupationally active | 91 (75.8) | 80 (66.1) |