Table 1 Characteristics of tegaserod initiators and comparators at baseline 1
Characteristic or Condition | Tegaserod initiators (N = 2,762) | Comparison cohort (N = 2,762) | ||
|---|---|---|---|---|
N | % | N | % | |
Age group | ||||
0-29 | 386 | 14.0% | 386 | 14.0% |
30-49 | 1,416 | 51.3% | 1,412 | 51.1% |
50+ | 960 | 34.8% | 964 | 34.9% |
Sex | ||||
Female | 2,496 | 90.4% | 2,435 | 88.2% |
Region | ||||
Northeast | 73 | 2.6% | 70 | 2.5% |
South & Southeast | 1,256 | 45.5% | 1,312 | 47.5% |
Midwest | 1,228 | 44.5% | 1,159 | 42.0% |
West | 205 | 7.4% | 221 | 8.0% |
Select Baseline Diagnoses | ||||
Abdomen / Pelvis Symptoms (ICD-9 789) | 1,413 | 51.2% | 1,417 | 51.3% |
Irritable Bowel Syndrome (ICD-9 564.1) | 1,150 | 41.6% | 1,117 | 40.4% |
Constipation (ICD-9 564.0) | 1,027 | 37.2% | 967 | 35.0% |
GI System Symptoms (ICD-9 787) | 886 | 32.1% | 1,050 | 38.0% |
Select Baseline Procedures | ||||
Surgical Pathology (CPT 88305) | 696 | 25.2% | 700 | 25.3% |
Colon Procedures (CPT | 643 | 23.3% | 665 | 24.1% |
CT Scan Abdomen (CPT 74150–74175) | 413 | 15.0% | 426 | 15.4% |
Abdominal Ultrasound (CPT | 381 | 13.8% | 401 | 14.5% |
Gallbladder Radiography (CPT | 84 | 3.0% | 66 | 2.4% |
Gallbladder Surgery (CPT | 46 | 1.7% | 42 | 1.5% |
Baseline Drug Classes Dispensed | ||||
Proton Pump Inhibitors | 1,029 | 37.3% | 1,059 | 38.3% |
Analgesics, Narcotics | 955 | 34.6% | 998 | 36.1% |
Serotonin Specific Reuptake Inhibitor | 692 | 25.1% | 686 | 24.8% |
Laxative Drugs | 533 | 19.3% | 522 | 18.9% |
Baseline Healthcare Utilization | Mean | Median | Mean | Median |
Total Cost ($) | 4,319.40 | 2,127.77 | 4,750.59 | 2,254.55 |
Physician Costs (US$) | 1,501.48 | 828.12 | 1,576.03 | 849.34 |
Cost of Pharmaceuticals (US$) | 923.33 | 461.04 | 937.55 | 405.71 |
Gastroenterologist Visits | 1.6 | 1 | 1.6 | 0 |
Number of Drug Classes Dispensed | 7.9 | 7 | 7.8 | 7 |