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Table 2 Overall SVR according to different variables

From: HCV genotype 1a shows a better virological response to antiviral therapy than HCV genotype 1b

Variable

N° of pts/Tot pts

SVR (%)

P value

Sex

   

F

68/145

46

ns

M

119/243

49

 

Age

   

< 50

123/210

58

0.00001

> 50

64/178

37

 

BMI

   

< 25

145/280

51

0.05

> 25

32/82

39

 

ALT

   

< 100

139/261

53

0.002

> 100

51/127

40

 

HCV-RNA

   

≤ 5 .60 log10

64/96

66

0.00004

> 5 .60 log10

123/292

42

 

Genotype

   

1a

91/165

55

0.02

1b

96/223

43

 

Staging*

   

≤ S3

142/262

54

0.00008

> S3

15/60

25

 

Drug

   

PegINF α 2b

100/195

51

ns

PegINF α 2a

87/193

45

 

RVR

   

Yes

129/160

80

0.000001

No

58/228

25

 
  1. Legend. SVR: sustained virological response, F: female, M:male, PegINF: pegylated interferon, BMI: body mass index, ALT: alanine aminotransferase value (IU/ml); RVR: rapid virological response.
  2. *322 over 388 patients were submitted to liver biopsy and analyzed for this variable.
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BMC Gastroenterology

ISSN: 1471-230X

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