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Table 3 The efflux capacity of the HCC cell lines in exporting Hoechst 33342

From: Gene and functional up-regulation of the BCRP/ABCG2 transporter in hepatocellular carcinoma

HCC lines Hoechst 33342 (μg/mL)
  2.5 5.0 10.0
HuH-7 100.0 ± 6.4 88.4 ± 5.5 53.0 ± 2.8
HepG2 100.0 ± 6.2 74.7 ± 3.1 51.2 ± 2.8
JHH-6 100.0 ± 5.8 80.1 ± 2.1 53.7 ± 4.0
  1. The increase of Hoechst 33342 concentration decreased intracellular dye accumulation in all HCC cell lines tested. The intracellular dye intake of 2.5 μg/mL as lowest dye concentration was considered as 100.0%. The data represented the mean ± SD of three independent experiments.