The expression of ABCG2 mRNA in HCC tissues. A. The general distribution of ABCG2 mRNA expression in HCC and normal liver. Normal liver (N; n = 7), cirrhotic tissue of HCC (n = 21), and tumoral tissue of HCC (n = 23). B. The up-regulation of ABCG2 mRNA in the HCC compared to its cirrhotic paired tissues from 15 paired individuals with histological G1/G2 and G3/G4 grade. The mRNA expression was normalized to reference genes β-actin and 18S-rRNA. A normal liver was considered as 1.0 au. Statistical student’s t test: ** p<0.01.