Table 3 Frequency of K8 variants observed in previously published studies
Patients cohort | Disease/ controls | #K8 G62C/ # subjects (%) | #K8 R341H/ # subjects (%) | Reference | |
|---|---|---|---|---|---|
France | ALC | 261 | 5 (1,9) | 8 (3,1) | This study |
Europe | Controls | 4167 | 65 (1,6) | - | [13] |
Germany | CHC | 278 | 5 (1,8) | 8 (2,9) | [18] |
US | End-stage liver disease | 274 | 4 (1,5) | 14 (5,1) | [19] |
Controls | 268 | 1 (0,373) | 8 (3,0) | ||
Germany | ALD | 215 | 4 (1,9) | - | [21] |
Controls | 679 | 12 (1,8) | |||
Germany | Controls | 560 | 9 (1,6) | - | [20] |
Italy | PBC | 201 | 4 (2,0) | 8 (4,0) | [5] |
Controls | 200 | 0 | 3 (1,5) | ||
US | ALF | 252 | 4 (1,6) | 18 (7,2) | [6] |