Table 6 The effects of alcohol drinking on the liver function tests by multivariable analyses ^a

1) History of alcohol drinking

None drinker

200.2 (192.0, 208.3)

7.13 (7.04, 7.21)

4.46 (4.41, 4.52)

68.6 (64.3, 72.9)

25.8 (23.0, 28.5)

28.7 (24.8, 32.7)

3.27 (3.13, 3.41)

1.00 (0.91, 1.10)

Past drinker, quit

189.2 (172.2, 206.4)

7.13 (6.94, 7.31)

4.49 (4.39, 4.60)

58.0 (49.2, 66.9) *

29.3 (23.5, 35.1)

28.6 (20.3, 37.0)

3.10 (2.81, 3.40)

1.00 (0.80, 1.19)

Current drinker

195.5 (188.7, 202.3)

7.08 (7.01, 7.16)

4.43 (4.39, 4.48)

64.0 (60.4, 67.5) *

25.0 (22.8, 27.3)

27.3 (24.0, 30.6)

3.43 (3.31, 3.55) *

1.07 (0.99, 1.14)

p for trend

0.269

0.291

0.225

0.037

0.514

0.441

0.016

0.156

2) Daily amount of alcohol (g)

No

199.8 (191.7, 207.9)

7.13 (7.05, 7.22)

4.46 (4.41, 4.52)

68.2 (63.9, 72.4)

26.7 (24.0, 29.5)

29.1 (35.1, 33.0)

3.23 (3.10, 3.37)

0.99 (0.89, 1.08)

Not heavy (< 60g/day for male, <20g/day for female)

194.1 (187.3, 200.9)

7.07 (7.00, 7.15)

4.44 (4.40, 4.48)

62.8 (59.3, 66.3) *

24.2 (21.9, 26.5)

26.3 (23.0, 29.6)

3.31 (3.20, 3.43)

1.06 (0.98, 1.13)

Heavy (≥ 60 g/day for male, ≥20 g/day for female)

199.2 (185.8, 212.5)

7.15 (7.01, 7.30)

4.45 (4.37, 4.54)

66.8 (59.9, 73.8)

30.4 (25.9, 34.9)

32.8 (26.3, 39.3)

4.00 (3.77, 4.22) *

1.14 (0.99, 1.29)

p for trend

0.412

0.593

0.471

0.111

0.963

0.939

<0.001

0.041

3) Duration of alcohol drinking (years)

<10

195.7 (188.1, 203.3)

7.12 (7.04, 7.20)

4.46 (4.41, 4.51)

67.1 (36.1, 71.1)

25.6 (23.0, 28.1)

26.7 (23.0, 30.4)

3.22 (3.09, 3.35)

1.00 (0.92, 1.09)

≥ 10

197.1 (190.1, 204.2)

7.10 (7.02, 7.17)

4.45 (4.41, 4.50)

63.1 (59.4, 66.8)

25.7 (23.3, 28.1)

28.7 (25.3, 32.5)

3.46 (3.34, 3.58) *

1.08 (1.00, 1.16)

p for trend

0.725

0.616

0.807

0.057

0.918

0.289

0.001

0.111

4) Lifetime amount of alcohol (x10 ³ g)

Never

200.1 (191.8, 208.4)

7.13 (7.04, 7.22)

4.47 (4.42, 4.52)

68.7 (64.3, 73.0)

25.5 (22.7, 28.3)

28.4 (24.4, 32.5)

3.20 (3.06, 3.34)

1.00 (0.90, 1.09)

Mild (<100 x10³ g for male, <35 x10³ g for female)

193.0 (185.4, 200.6)

7.10 (7.02, 7.18)

4.56 (4.41, 4.50)

64.3 (60.3, 68.3) *

24.5 (22.0, 27.1)

27.5 (23.8, 31.2)

3.24 (3.11, 3.37)

1.07 (0.99, 1.09)

Moderate (100–200 x10³ g for male, 35–70 x10³ g for female)

203.6 (191.4, 215.8)

7.00 (6.87, 7.13)

4.44 (4.36, 4.51)

59.9 (53.5, 66.2) *

23.6 (19.5, 27.7)

23.4 (17.4, 29.3)

3.35 (3.14, 3.56)

0.97 (0.83, 1.11)

Heavy (≥200 x10³ g for male, ≥70 x10³ g for female)

195.4 (186.5, 204.3)

7.12 (7.02, 7.21)

4.44 (4.38, 4.50)

62.6 (58.0, 67.3) *

27.7 (24.7, 30.7)

38.8 (24.5, 33.1)

3.68 (3.53, 3.83) *

1.08 (0.98, 1.18)

p for trend

0.679

0.618

0.329

0.026

0.237

0.929

<0.001

0.316