From: Esophageal motility, vagal function and gastroesophageal reflux in a cohort of adult asthmatics
 | Asthmatics with negative GERD symptom scores (n = 10) | Asthmatics with positive GERD symptom scores (n = 20) | All asthmatics (n = 30) |
---|---|---|---|
Age, yrs mean ± SD | 35.4 ± 9.6 | 34.5 ± 8.0 | 34.8 ± 8.4 |
Gender, (M:F) | 2:8 | 9:11 | 12:18 |
BMI, (kg/m2), mean ± SD | 20.3 ± 2.4 | 21.9 ± 5.1 | 21.3 ± 4.4 |
GERD symptom score, mean ± SD* | 10.0 ± 1.6 | 43.1 ± 17.0 | 32.0 ± 21.1 |
Upper GI endoscopy status, no of subjects ** | Â | Â | Â |
Normal | 5 | 12 | 17 |
Esophagitis, grade 1 | 2 | 7 | 9 |
Esophagitis, grade 2 | - | - | - |
Esophagitis, grade 3 | - | 1 | 1 |
Severity of asthma, no of subjects (%) | Â | Â | Â |
Mild intermittent | 10 (100) | 16 (80) | 26 (87) |
Mild persistent | - | 4 (20) | 4 (13) |
On oral drugs, no of subjects (%) | Â | Â | Â |
Oral salbutamol | 6 (60) | 11 (55) | 17 (57) |
Inhaled salbutamol | 4 (40) | 5 (25) | 9 (30) |
Oral theophylline | 5 (50) | 6 (30) | 11 (37) |
Oral steroids | 4 (40) | 7 (35) | 11 (37) |
Inhaled steroids | 4 (40) | 10 (50) | 14 (47) |
Spirometry results, mean ± SD |  |  |  |
FVC | 3.2 ± 0.4 | 3.2 ± 0.6 | 3.2 ± 0.5 |
FEV1 | 2.7 ± 0.5 | 2.7± 0.4 | 2.7 ± 0.4 |
FEV1/FVC % | 85.2 ± 9.5 | 82.9 ± 11.0 | 83.7 ± 10.4 |