Table 2 Summary Sensitivities and Specificities of the APRI at various Diagnostic Thresholds for Prediction of Significant Fibrosis and Cirrhosis
Test Threshold and Outcome | Number of Studies (Patients) | Summary Sensitivity (95% CI) | Summary Specificity (95% CI) |
|---|---|---|---|
Significant Fibrosis | Â | Â | Â |
0.5 | 5(788) | 84%(81%-88%) | 41%(36%-46%) |
1.5 | 5(788) | 49%(44%-53%) | 84%(80%-88%) |
Cirrhosis | Â | Â | Â |
1-1.5 | 6(1248) | 54%(48%-60%) | 78%(75%-80%) |
2 | 4(792) | 28%(21%-35%) | 87%(84%-89%) |