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Table 3 Adjusted health care costs during 12-month period following 5-ASA initiation, by 5-ASA adherence status

From: Association between oral 5-ASA adherence and health care utilization and costs among patients with active ulcerative colitis

Cost Outcome

5-ASA Adherence Status

Adherent

Not Adherent

Mean Predicted Costa

95% Confidence Interval

Mean Predicted Costa

95% Confidence Interval

PValue

Cost of inpatient admissions

$14,541.65

[$14,313.80, $14,769.49]

$28,726.65

[$28,443.11, $29,010.19]

<0.0001

Cost of ER visits

$495.33

[$477.91, $512.76]

$635.95

[$621.95, $649.94]

<0.0001

Cost of outpatient office visits

$1,081.83

[$1,046.79, $1,116.87]

$1,145.67

[$1,121.99, $1,169.35]

0.0031

Cost of other outpatient/ ancillary visits

$3,702.39

[$3,602.08, $3,802.70]

$4,923.29

[$4,837.67, $5,008.91]

<0.0001

Cost of pharmacy prescriptions

$5,309.84

[$5,180.82, $5,438.86]

$3,189.88

[$3,142.40, $3,237.35]

<0.0001

Cost of UC-related pharmacy prescriptions

$3,568.57

[$3,519.87, $3,617.27]

$1,718.20

[$1,702.68, $1,733.73]

<0.0001

Cost of non–UC-related pharmacy prescriptions

$1,845.51

[$1,746.93, $1,944.09]

$1,541.60

[$1,487.04, $1,596.17]

<0.0001

Cost of non-pharmacy visits

$8,101.24

[$7,848.17, $8,354.30]

$14,226.32

[$13,936.79, $14,515.85]

<0.0001

Cost of total visits

$13,464.89

[$13,094.43, $13,835.35]

$17,339.36

[$17,033.28, $17,645.45]

<0.0001

  1. 5-ASA = 5-aminosalicylate; ER = emergency department; UC = ulcerative colitis.
  2. aPredicted costs are based on generalized linear models and control for age, gender, geographic region, health plan type, payer type, and Charlson Comorbidity Index scores. Separate models were run for each cost sector; therefore, the mean predicted cost for each sector does not sum up to the total predicted cost.