Association between oral 5-ASA adherence and health care utilization and costs among patients with active ulcerative colitis

Table 1 Characteristics of the study population, by 5-ASA adherence status

Characteristic	All 5-ASA Initiators		Adherence Status				PValue^a
	All 5-ASA Initiators		Not Adherent		Adherent
	n	%	n	%	n	%
n (row%)	1693	100.00	1217	100.00	476	100.00
Gender
Female	840	49.62	628	51.60	212	44.54	0.0090
Male	853	50.38	589	48.40	264	55.46	—
Age
Mean (SD)	42.3 (12.8)		42.4 (12.8)		42.2 (12.9)		0.7675
Median	42		42		43.5
Range (minimum, maximum)	(18, 93)		(18, 93)		(18, 78)
Distribution (years)
18-24	165	9.75	112	9.20	53	11.13	0.2283
25-44	775	45.78	576	47.33	199	41.81	0.0403
45-54	433	25.58	304	24.98	129	27.10	0.3684
55-64	280	16.54	191	15.69	89	18.70	0.1349
65+	40	2.36	34	2.79	6	1.26	0.0619
Geographic region
East	354	20.91	260	21.36	94	19.75	0.4623
Midwest	759	44.83	528	43.39	231	48.53	0.0113
South	306	18.07	238	19.56	68	14.29	0.0557
West	274	16.18	191	15.69	83	17.44	0.3815
Health plan type
HMO	629	37.15	442	36.32	187	39.29	0.2561
Indemnity	39	2.30	30	2.47	9	1.89	0.4788
POS	261	15.42	181	14.87	80	16.81	0.3218
PPO	681	40.22	505	41.50	176	36.97	0.0881
Unknown	30	1.77	21	1.73	9	1.89	0.8168
Multiple types	53	3.13	38	3.12	15	3.15	0.9756
Payer type
Commercial	1423	84.05	1020	83.81	403	84.66	0.6672
Medicaid	18	1.06	15	1.23	3	0.63	0.2774
Medicare	48	2.84	40	3.29	8	1.68	0.0735
Self-insured	56	3.31	37	3.04	19	3.99	0.3251
Medigap	2	0.12	2	0.16	0	0.00	0.3762
Unknown	144	8.51	101	8.30	43	9.03	0.6262
Multiple types	2	0.12	2	0.16	0	0.00	0.3762
CCI score
Mean (SD)	1.23 (1.60)		1.18 (1.59)		1.36 (1.62)		0.0378
Median	0		0		0
Range (minimum, maximum)	(0, 9)		(0, 9)		(0, 8)

5-ASA = 5-aminosalicylate; CCI = Charlson Comorbidity Index; HMO = health maintenance organization; POS = point of service; PPO = preferred provider organization; SD = standard deviation.
^aChi-square tests for categorical variables, t-tests for continuous variables.

ISSN: 1471-230X