Obesity is an independent risk factor for pre-transplant portal vein thrombosis in liver recipients

BMC Gastroenterology

Table 3 Clinical thrombophilic risk factors in association with pre-transplant PVT cases

	With pre-transplant PVT (n = 62)	Without pre-transplant PVT (n = 318)	Significance
Child/adult recipient	2/60	48/270	p = 0.011
Male/female recipient	44/18	210/108	p = 0.451
Associated tumor (Yes/No)	15/32	63/133	p = 0.951
Diabetes mellitus and/or high lipid (Yes/No)	24/25	68/135	p = 0.043
Inflammatory disease (Yes/No)	0/39	0/183	p = N
Smoking (Yes/No)	20/26	111/92	p = 0.169
Inmobility (Yes/No)	3/36	9/166	p = 0.531
Surgery Intervention (Yes/No)	24/23	104/103	p = 0.919
Obesity (Yes/No)	5/37	4/178	p = 0.004
Nephrotic syndrome (Yes/No)	0/39	14/163	p = 0.069
Myeloproliferative syndrome (Yes/No)	2/39	0/185	p = 0.003
Trauma (Yes/No)	3/37	10/171	p = 0.631
Cause of liver transplantation			p = 0.135
BHV	2	16
CHV	12	61
Ethanol	14	48
Autoimmune	3	5
Toxicity	1	7
Tumor	7	22
Cryptogenetic	1	14
Vascular	2	0
Infrequent (deficit alpha1 antitrypsin)	3	23
Biliary atresia	2	22
BHV and CHV	10	42
BHV and CHV and Tumor	5	58

HCV, hepatitis C virus; HBV, hepatitis B virus; PVT, portal vein thrombosis. Data on height was available in 224 of 380 recipients. The body mass index (BMI) was calculated as weight in kilograms/height in meters squared. Obesity was considered when BMI > 30 kg/m2. Missing Values: associated tumor (138); DM and/or High lipid (128); Inflammatory disease (158); Smoking (131); Inmobility (166); Surgery Intervention (126); Nephrotic Syndrome (164); Myeloproliferative Syndrome (159); Trauma (159).

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