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Table 4 Reproductive history of female PBC patients, FDR and Controls

From: Primary Biliary Cirrhosis in a genetically homogeneous population: Disease associations and familial occurrence rates

  Controls N =127 PBC N = 94 PBC vs Controls p-value FDR N = 75 FDR vs Controls p-value
Mean age at menarche 13 ± 1.6 13.13 ± 1.4 NS 13.1 ± 1.35 NS
Mean age at last period 49.2 ± 4.6 48.6 ± 4.8 NS 46.6 ± 5.9 0.039*
Mean age at first pregnancy 24.9 ± 4.8 24.3 ± 4.7 NS 23.35 ± 4.7 NS
Mean duration of period 5.1 ± 1.2 5.3 ± 1.6 NS 5.35 ± 1.2 NS
Number of pregnancies 2.8 ± 2 2.9 ± 1.6 NS 2.1 ± 1.9 0.018*
Number of children 2 ± 1.1 2.2 ± 1.1 NS 1.6 ± 1.3 0.009*
Normal child birth 74.8% 84% NS 61.6% NS
Caesarean section 15.7% 12.8% NS 21.9% NS
Miscarriage 27.6% 29.8% NS 20.5% NS
Abortion 12.6% 13.8% NS 15.1% NS
HRT 10.2% 16.3% NS 26% 0.005*
Hysterectomy 10.2% 17% NS 8.2% NS
Ovariectomy 14.2% 18.1% NS 13.7% NS
Uterine fibroids 20.5% 21.3% NS 9.6% 0.05*
Vaginal infection 28.3% 23.3% NS 42.5% 0.045*
  1. * Statistically significant.