Table 4 Reproductive history of female PBC patients, FDR and Controls
|  | Controls N =127 | PBC N = 94 | PBC vs Controls p-value | FDR N = 75 | FDR vs Controls p-value |
|---|---|---|---|---|---|
Mean age at menarche | 13 ± 1.6 | 13.13 ± 1.4 | NS | 13.1 ± 1.35 | NS |
Mean age at last period | 49.2 ± 4.6 | 48.6 ± 4.8 | NS | 46.6 ± 5.9 | 0.039* |
Mean age at first pregnancy | 24.9 ± 4.8 | 24.3 ± 4.7 | NS | 23.35 ± 4.7 | NS |
Mean duration of period | 5.1 ± 1.2 | 5.3 ± 1.6 | NS | 5.35 ± 1.2 | NS |
Number of pregnancies | 2.8 ± 2 | 2.9 ± 1.6 | NS | 2.1 ± 1.9 | 0.018* |
Number of children | 2 ± 1.1 | 2.2 ± 1.1 | NS | 1.6 ± 1.3 | 0.009* |
Normal child birth | 74.8% | 84% | NS | 61.6% | NS |
Caesarean section | 15.7% | 12.8% | NS | 21.9% | NS |
Miscarriage | 27.6% | 29.8% | NS | 20.5% | NS |
Abortion | 12.6% | 13.8% | NS | 15.1% | NS |
HRT | 10.2% | 16.3% | NS | 26% | 0.005* |
Hysterectomy | 10.2% | 17% | NS | 8.2% | NS |
Ovariectomy | 14.2% | 18.1% | NS | 13.7% | NS |
Uterine fibroids | 20.5% | 21.3% | NS | 9.6% | 0.05* |
Vaginal infection | 28.3% | 23.3% | NS | 42.5% | 0.045* |