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Table 3 Laboratory features of FDR with abnormal LFT

From: Primary Biliary Cirrhosis in a genetically homogeneous population: Disease associations and familial occurrence rates

Index patient Relation Age ALT γGT ALP TBil IgM ANA AMA Autoimmune Diseases Diagnosis of liver disease
XN Sister 65 24 34 161 0.61 201 - 1:320/M2 None PBC
DA Sister 76 65 527 816 1.29 1360 - 1:160/M2 None PBC
MD Mother 55 90 213 362 4.7 303 1:80MND 1:160/M2 None PBC
PK Sister 67 49 57 140 1.4 296 1:80MND 1:320/M2 Sarcoidosis PBC
BK Son 43 57 39 90 1.43 81.9 - - None Liver steatosis
Daughter 51 17 15 63 0.85 238 - 1:160/M2 Hashimoto PBC
D Mother 80 21 57 111 0.79 250 1:640 - None Refused f-up
Brother 50 56 152 95 0.68 180 - 1:160/M2 None PBC
TM Daughter 29 89 33 126 0.3 193 1:80 - None AIC
PE Daughter 43 16 11 191 0.53 211 - - Hashimoto, MS Refused f-up
Son 54 37 36 156 0.64 189 - - Hashimoto Refused f-up
AT Daughter 44 27 55 68 0.5 132 - - None Nothing found
KA Brother 54 24 61 58 0.41 120 - - None Nothing found
KX Son 43 58 16 56 0.65 35 - - None Nothing found
ZP Daughter 56 83 27 102 0.42 114 - - RA,HistiocytosisB Nothing found
KF Son 25 62 27 69 1.1 102 - - None Liver Steatosis
B Son 38 72 61 99 0.51 54.2 - - None Liver Steatosis
M Son 53 17 56 55 1.47 - - - None Alcohol abuse
ST Brother 34 35 54 60 0.48 89.6 - - None Liver steatosis
Son 22 74 16 42 0.5 90.2 - - None Alcohol abuse
L Son 44 79 87 84 0.83 208 - - None Refused f-up
TX Son 55 36 44 188 0.85 34 - - None Liver Steatosis
Z Daughter 18 89 31 118 0.3 - - - None EBV infection
  1. Normal values: AST 8-40U/l, ALT 8-40U/l, γGT 10-50U/l, ALP 40-150U/I, Bilirubin 0.1-1.3 mg/dl, IgM 25-170 mg/dl. In bolded numbers are values over the normal range.