Skip to main content

Table 1 Determinants of Health Related Quality of Life on t = 0 and course of Health Related Quality of Life

From: Long-term effects of treatment and response in patients with chronic hepatitis C on quality of life. An international, multicenter, randomized, controlled study

 

Subscale

t = 0

P-value

Course

(follow up - t = 0)

P-value

Age

 

Age category (20-29, 30-39, 40-9, 50-59)

 

Age category (20-29, 30-39, 40-49,50-59)

 
 

Physical functioning

90.6, 93.1, 86.1, 78.1

0.01

   
 

Subscale

t = 0

P-value

Course

(follow up - t = 0)

P-value

Cirrhosis No/Yes

 

No

Yes

 

No

Yes

 
 

Mental component summary scale

44.7

53.7

0.001

   
 

General health

61.3

73.5

0.003

   
 

Bodily pain

74.2

88.4

0.04

   
 

Role limitation because of emotional problems

68.9

88.1

0.05

   
 

Mental health

66.4

80.4

0.0004

   
 

Subscale

t = 0

P-value

Course

(follow up - t = 0)

P-value

Income in Euros

Subscale SF-36

Correlation coefficient

P-value

Correlation coefficient

P-value

 

Physical component summary scale

0.30

0.003

   
 

Role limitation because of physical health

0.23

0.002

   
 

Vitality

   

.30

0.02

 

Bodily pain

0.18

0.07

   
 

Mental health

   

.21

0.03

 

Subscale

t = 0

P-value

Course

(Follow up - t = 0)

P-value

Gender (M/F)

 

M

F

 

M

F

 
 

Bodily pain

   

+ 4.1

- 7.2

0.02

 

Social functioning

   

+ 6.3

- 5.8

0.008

 

Vitality

   

+ 7.2

- 2.7

0.03

 

Role limitation because of emotional problems

   

+ 9.3

- 8.3

0.05

  1. Results of statistical analysis of the influence of age (ANOVA), presence of cirrhosis (t-test), gender (t-test) and income in Euros (correlation analysis: Spearman) on Health Related Quality of Life at start of treatment (t = 0) and the course of Health Related Quality of Life (scores at 24 weeks after treatment (Follow up) minus scores at baseline). Data were shown if relationships were statistically significant.