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Table 1 Determinants of Health Related Quality of Life on t = 0 and course of Health Related Quality of Life

From: Long-term effects of treatment and response in patients with chronic hepatitis C on quality of life. An international, multicenter, randomized, controlled study

  Subscale t = 0 P-value Course (follow up - t = 0) P-value
Age   Age category (20-29, 30-39, 40-9, 50-59)   Age category (20-29, 30-39, 40-49,50-59)  
  Physical functioning 90.6, 93.1, 86.1, 78.1 0.01    
  Subscale t = 0 P-value Course (follow up - t = 0) P-value
Cirrhosis No/Yes   No Yes   No Yes  
  Mental component summary scale 44.7 53.7 0.001    
  General health 61.3 73.5 0.003    
  Bodily pain 74.2 88.4 0.04    
  Role limitation because of emotional problems 68.9 88.1 0.05    
  Mental health 66.4 80.4 0.0004    
  Subscale t = 0 P-value Course (follow up - t = 0) P-value
Income in Euros Subscale SF-36 Correlation coefficient P-value Correlation coefficient P-value
  Physical component summary scale 0.30 0.003    
  Role limitation because of physical health 0.23 0.002    
  Vitality     .30 0.02
  Bodily pain 0.18 0.07    
  Mental health     .21 0.03
  Subscale t = 0 P-value Course (Follow up - t = 0) P-value
Gender (M/F)   M F   M F  
  Bodily pain     + 4.1 - 7.2 0.02
  Social functioning     + 6.3 - 5.8 0.008
  Vitality     + 7.2 - 2.7 0.03
  Role limitation because of emotional problems     + 9.3 - 8.3 0.05
  1. Results of statistical analysis of the influence of age (ANOVA), presence of cirrhosis (t-test), gender (t-test) and income in Euros (correlation analysis: Spearman) on Health Related Quality of Life at start of treatment (t = 0) and the course of Health Related Quality of Life (scores at 24 weeks after treatment (Follow up) minus scores at baseline). Data were shown if relationships were statistically significant.