Longitudinal fluctuations in PD1 and PD-L1 expression in association with changes in anti-viral immune response in chronic hepatitis B

Table 1 Patients demographic data and levels of serum markers at time of initial presentation

Patient no.	Gender	Level of serum ALT ( IU/L)	Level of serum HBsAg (ng/mL)	HBV-DNA (copies/mL)	Expression of HLA-A₂
1	male	200	527	1 × 10⁷	positive
2	male	120	513	1.5 × 10⁷	positive
3	male	135	468	6.3 × 10⁶	positive
4	female	122	491	6.1 × 10⁶	positive
5	male	150	132	8.7 × 10⁶	positive
6	female	132	401	1.3 × 10⁵	positive
7	female	197	401	5.1 × 10⁶	positive
8	male	200	441	1.1 × 10⁵	positive
9	male	101	356	7.5 × 10⁴	positive
10	female	157	437	3.3 × 10⁶	positive
11	male	156	491	2.0 × 10⁵	positive
12	female	189	411	7.0 × 10⁵	positive
13	female	172	328	5.4 × 10⁶	positive
14	male	194	396	1.9 × 10⁶	positive
15	female	200	567	1.1 × 10⁷	positive

Abbreviations: ALT, alanine transaminase; HBsAg, hepatitis B surface antigen; HBV, hepatitis B virus; HLA, human leukocyte antigen.

ISSN: 1471-230X