Effects of patient factors on noninvasive liver stiffness measurement using acoustic radiation force impulse elastography in patients with chronic hepatitis C

Table 1 Patient characteristics

Variable	METAVIR F0-3	METAVIR F4	P value
Variable	n = 109	n = 18	P value
Age, year	51.6(1.2)	62.7(1.5)	<.001
Gender (n)			1.000
Male	51	8
Female	58	10
BMI, kg/m²	24.64(0.33)	24.02(0.79)	.477
HCV genotype (n)			1.000
1	53	9
Non-1	56	9
HCV RNA, x 10⁶, copies/mL	8.16(1.21)	1.02(0.52)	<.001
ALT, IU/L	97.94(8.24)	64.28(8.07)	.005
ALT/ULN (n)			.273
<1x	26	5
≧1x <2x	35	7
≧2x <3x	21	5
≧3x <4x	7	1
≧4x	20	0
ActiTest, A score	0.51(0.03)	0.51(0.06)	.928
Bilirubin, umol/L	16.80(0.54)	22.36(2.00)	<.001
Cr, umol/L	71.80(4.34)	65.42(4.35)	.301
INR	1.02(0.01)	1.12(0.03)	<.001
Na, meq/L	137.90(0.24)	137.83(0.60)	.918
Platelet, x 10⁹/L	176.61(5.67)	121.44(9.73)	<.001
Child-Pugh grade (n)
A		16
B		2
C
METAVIR F (n)
F0	0
F1	46
F2	40
F3	23
F4		18
METAVIR A (n)			.484
A0	31	3
A1	60	10
A2	16	5
A3	2	0
Hepatic steatosis (n)			1.000
S0	15	2
S1	37	6
S2	52	10
S3	4	0
S4	1	0
Liver SWV, m/s	1.65(0.06)	2.62(0.19)	<.001
FibroTest, F score	0.57(0.03)	0.79(0.04)	<.001

Continuous variables were presented as mean (standard error) and examined using the Student’s t test. Categorical variables were estimated using Fisher’s exact test. ALT, serum alanine aminotransferase; Cr, serum creatinine; INR, international normalized ratio of prothrombin time; METAVIR A, activity; METAVIR F, fibrosis; Na, serum sodium; SWV, shear wave velocity.

ISSN: 1471-230X