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Table 4 Subgroup characteristics of patients with pathological pepsinogen test

From: Serological assessment of gastric mucosal atrophy in gastric cancer

   PG1 < 70 μg/ml   PG1/2-ratio < 3.0  
   Positive (n = 47) Negative (n = 71) p-value Positive (n = 20) Negative (n = 98) p-value
Laurén type Intestinal 28 (59.6%) 31 (43.7%) n.s. 14 (70%) 45 (45.9%) n.s.
  Diffuse 19 (40.4%) 40 (56.3%)   6 (30%) 53 (54.1%)  
Localisation Proximal 19 (40.4%) 34 (47.9%) n.s. 11 (55%) 42 (42.9%) n.s.
  Distal 28 (59.6%) 37 (52.1%)   9 (45%) 56 (57.1%)  
H. pylori (positive) 40 (85.1%) 59 (83.1%) n.s. 17 (85%) 82 (83.7%) n.s.
CagA (positive) 34 (72.3%) 43 (60.6%) n.s. 15 (75%) 62 (63.3%) n.s.
IM (positive) 39 (83.0%) 47 (66.2%) 0.057 16 (80%) 70 (71.4%) n.s.
Atrophy* (positive) 25 (53.2%) 18 (25.4%) 0.003 12 (60%) 31 (31.6%) 0.022
  1. Displayed are absolute numbers as well as percentages with respect to the group with the same test result (PG test positive or negative). Significant differences are marked with an asterisk applying a two-sided significance level of p < 0.05.