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Table 1 Histopathological grading scores

From: Role of inducible nitric oxide synthase pathway on methotrexate-induced intestinal mucositis in rodents

Scores Microscopic findings
0 Normal histological findings
1 Mucosa: villus blunting, loss of crypt architecture, sparse inflammatory cell infiltration, vacuolization and edema. Normal muscular layer
2 Mucosa: villus blunting with fattened and vacuolated cells, crypt necrosis, intense inflammatory cell infiltration, vacuolization and edema Normal muscular layer
3 Mucosa: villus blunting with fattened and vacuolated cells, crypt necrosis, intense inflammatory cell infiltration, vacuolization and edema Muscular: edema, vacuolization, sparse neutrophil infiltration