Table 1 Major features of the 14 exclusively breast-fed infants with allergic proctocolitis
Patient (sex) | Clinical Onset | Maternal elimination. diet (*) | Our observation | Atopy patch test | Endoscopic features | Histology Eosinophiles 10HPF (40x) | Current status (age) | |||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Â | Age (days) | Symptoms | Allergen avoidance | Duration | Age (days) | Symptoms | Â | Baseline | Follow-up (**) | Baseline | Follow-up (**) | Â |
1 (F) | 60 | Haematochezia; GERD | CM S | 4 weeks | 90 | Severe rectal bleeding; syderopenic anemia | BM ++++ CM + | Scattered erosions; ileo-colonic LNH | Normal mucosa | > 60 | Normal features | Free diet, well (by 3 years) |
2 (M) | 90 | Haematochezia; GERD | CM E S | 8 weeks | 180 | Melena; hematemesis | BM +++ CM ++ | Diffuse erosions; ileal LNH | Mild LNH | > 60 | Normal features | Free diet, well (by 2 years) |
3 (M) | 120 | Chronic diarrhea | CM E | 6 weeks | 160 | Severe rectal bleeding | BM ++ S + | Scattered erosions; ileo-colonic LNH | Mild LNH | > 60 | Normal features | Free diet, well (by 2 years) |
4 (M) | 10 | Blood and mucus in stools | CM E S | 3 weeks | 30 | Hematochezia | BM +++ CM + E + | Friability; initial LNH | Normal mucosa | 40-50 | Normal features | CM and E-free diet (13 months) |
5 (M) | 20 | Bloody diarrhea | CM | 1 week | 30 | Bloody diarrhea; syderopenic anemia | BM ++ | Scattered erosions; initial LNH | Normal mucosa | 40-50 | Normal features | Free diet, well (by 15 months) |
6 (F) | 20 | Hematochezia; GERD | CM S | 9 weeks | 120 | Diarrhea; mucus in stools | BM +++ | Diffuse LNH | Mild LNH | > 60 | Normal features | CM and E-free diet (11 months) |
7 (M) | 7 | Fluid diarrhoea and feeding refusal | CM E | 1 week | 15 | Hematochezia | CM ++ R + | Rectal erosions | Normal mucosa | 40-50 | Normal features | CM and R-free diet (7 months) |
8 (M) | 180 | Haematochezia | CM E S | 2 weeks | 195 | Severe rectal bleeding; dehydration | BM + CM ++ E ++ S ++ W + R ++ | Diffuse LNH | Normal mucosa | > 60 | Normal features | CM, S, E and R-free diet (15 months) |
9 (F) | 40 | Blood and mucus in stools | CM E | 3 weeks | 60 | Hematochezia | BM ++++ | Hedema; hyperhemia; scattered erosions | Normal mucosa | 40-50 | Normal features | CM and E-free diet (16 months) |
10 (M) | 28 | Blood and mucus in stools; colics | CM E S | 4 weeks | 60 | Bloody diarrhea; mucus in stools | BM ++ S ++ | Diffuse erosions; ileo-colonic LNH | Normal mucosa | > 60 | Normal features | Free diet, well (by 1 year) |
11 (M) | 30 | Blood and mucus in stools; colics | CM S | 4 weeks | 60 | Severe rectal bleeding; colics | BM +++ CM + | Scattered erosions; friability; ileo-colonic LNH | Normal mucosa | 40-50 | Normal features | Free diet, well (by 1 year) |
12 (F) | 45 | Diarrhea with mucus and blood; irritability | CM E S | 6 weeks | 60 | Severe rectal bleeding | BM +++ CM + S + | Scattered erosions; ileo-colonic LNH | Mild LNH | 40-50 | Normal features | Free diet, well (by 1 year) |
13 (M) | 20 | Blood and mucus in stools; colics | CM | 1 week | 30 | Bloody diarrhea; mucus in stools | BM + E + | Scattered erosions; friability ileo-colonic LNH | Normal mucosa | > 60 | Normal features | CM and E-free diet (14 months) |
14 (M) | 21 | Diarrhea with mucus and blood; irritability | CM E S | 1 week | 30 | Bloody diarrhea; irritability | BM++ | Diffuse erosions; ileal LNH | Normal mucosa | > 60 | Normal features | Free diet, well (by 1 year) |