Table 1 Patients classified as a probable or possible based on paracetamol score (RUCAM algorithm).
Use of paracetamol | |||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Case | Sex/Age | Alcohol use (g/d) | ALT/AP | Bili | Pattern of ALI | Hypersensitivity | Outcome | Indication | Daily dose (mg) | Pattern of use | RUCAM Score | Concomitant drugs | RUCAM Score |
Probable (6 to 8) | |||||||||||||
1 | F/58 | 43 | 15.85/1.74 | 1.36 | HC | No | Tx | Osteoarthritis | 650 | Once a week for years till day before ALI. | 8 | ||
Dexchlorpheniramine | 7 | ||||||||||||
2 | F/82 | 0 | 15.32/1.95 | 10.41 | HC | Thrombocytopenia | Recovered | Cold | 650 | Daily for 10 days before ALI. | 7 | ||
Metamizol | 6 | ||||||||||||
Dextromethorphan | 6 | ||||||||||||
Chlorphenamine | 6 | ||||||||||||
Indapamide | 6 | ||||||||||||
Indomethacin | 6 | ||||||||||||
Tocopherol | 5 | ||||||||||||
3 | F/85 | 0.5 | 22.21/1.27 | 12.32 | HC | Arthralgia, thrombocytopenia | Not recovered | Osteoarthritis | 1950 | Daily for 22 days before ALI. | 7 | ||
Corticosteroids | 6 | ||||||||||||
4 | F/25 | 24 | 383.33/2.35 | 3.64 | HC | Eosinophilia | Recovered | Cephalea | 3250 | Daily for 2 days before ALI. | 7 | ||
Metoclopramide | 6 | ||||||||||||
Bisacodyl | 6 | ||||||||||||
Possible (3 to 5) | |||||||||||||
5 | M/18 | 13 | 5.27/1.24 | 5.88 | M | Fever | Recovered | Cephalea | 650 | 1 day, 11 days before ALI. | 5 | ||
Budesonide | 3 | ||||||||||||
6 | F/23 | 13 | 50.23/2.16 | 9.23 | HC | Fever, rash | Recovered | Cephalea | 500 | 1 day, 2 months before ALI. | 4 | ||
Fever | 1950 | 1 day, 3 months before ALI. | |||||||||||
Fever | 1950 | 3 days, between day 21 and day 13 before ALI. | |||||||||||
Carbocysteine | 3 | ||||||||||||
Ambroxol | 3 | ||||||||||||
Benzocaine | 3 | ||||||||||||
Chlorhexidine | 3 | ||||||||||||
7 | F/35 | 20 | 61.10/0.64 | 22.43 | HC | No | Recovered | Dysmenorrhea | 650 | Once a month for last year till 11 days before ALI. | 3 | No | - |