Figure 2From: Early stage transplantation of bone marrow cells markedly ameliorates copper metabolism and restores liver function in a mouse model of Wilson disease Effect of BM cells transplantation on copper accumulation in the liver. The liver copper levels were measured by atomic absorption spectrophotometry in recipient livers from tx mice at 1, 4, 8 and 12 weeks post-transplant. (A) Copper levels in mice treated with DL BM cells or saline or tx BM cells transplantation at 2 months of age. (B) Copper levels in mice treated with DL BM cells or saline or tx BM cells transplantation at 5 months of age (n = 10). Values were mean ± SD and analyzed using ANOVA. *P < 0.05, compared with the saline-treated group; ▲P < 0.05, compared with the tx BM cells treated group.Back to article page